Information on Hodgkin's Lymphoma from the National Institutes of Health (NIH)
Hodgkin's lymphoma is a cancer of lymph tissue found in the lymph nodes, spleen, liver, bone marrow, and other sites. The first sign of this cancer is often an enlarged lymph node which appears without a known cause. The disease can spread to nearby lymph nodes. Later it may spread to the spleen, liver, bone marrow, or other organs. From Medline Plus, a service of the US National Library of Medicine and the National Institutes of Health.
Information on Hodgkin's Lymphoma at MD Anderson Cancer Center
Hodgkin's lymphoma, also known as Hodgkin's disease, usually develops in the lymphatic system (a part of the body's immune system). More information available from the MD Anderson Cancer Center.
Information on Hodgkin's Lymphoma from Memorial Sloan-Kettering Cancer Center
Hodgkin lymphoma is a cancer that originates in the lymph nodes. These nodes are a part of the lymphatic system, the collection of organs, tissues, and vessels that produces infection-fighting cells and carries them throughout the body. More information available from the Memorial Sloan-Kettering Cancer Center.
Know Your Nodes - Quiz
Many have heard of lymph nodes and know they are somewhere in the body, but beyond that, details about the lymphatic system and lymphoma often remain a mystery. Take some time to take the quiz, provided by Lymphoma Foundation Canada.
Video: Lymphoma
Lymphoma with Dr. Rick Hagemeister, a video presented by the MD Anderson Cancer Center.
Video: Lymphoma Treatment
There are 71,000 new cases of lymphoma diagnosed annually in the United States. Learn about new drug developments and innovative treatments such as vaccine therapy and bone marrow transplants. Listen to the webcast, presented by the MD Anderson Cancer Center.
Video: Lymphoma
Dr. Rick Hagemeister and his patient, Bill, in a video presented by the MD Anderson Cancer Center.
Video: Bone Marrow Donation
Stem cells or bone marrow could save someone's life. Elisè Collins, Dana-Farber's Donor Center manager, and Joseph Antin, MD, Chief of the Stem Cell Transplant Program at Dana-Farber/Brigham and Women's Cancer Center, explain how you can help. A video presented by the Dana-Farber Cancer Institute.
Video: Leukemia and Lymphoma Society present Team In Training
Every five minutes, someone in the United States learns that he or she has leukemia, Hodgkin or non-Hodgkin lymphoma or myeloma. Every ten minutes, someone dies of a blood cancer. In exchange for training and support, you help raise money towards cures for blood cancers like leukemia -- the No. 1 disease killer of children -- lymphoma and myeloma. Watch the video from the Leukemia and Lymphoma Society.
Hodgkin's Disease Treatment: Recommendation Statement
Despite the excellent predictive value of the Ann Arbor staging system for Hodgkin's disease, it has been shown that certain presentations of stage I-II may be associated with a distinctly worse freedom from progression when initial treatment is with irradiation alone. More intensive management approaches are indicated for some of these patients. See National Guideline Clearinghouse major recommendations.
Follow-up of Hodgkin’s Disease: Recommendation Statement
Routine follow-up evaluation for Hodgkin's disease after completion of treatment and response assessment. See National Guideline Clearinghouse major recommendations.
Hodgkin’s disease staging evaluation: Recommendation Statement
Staging evaluation for patients with Hodgkin's disease. See National Guideline Clearinghouse major recommendations.
Clinicopathologic and molecular features of Hodgkin's lymphoma.
Hodgkin's lymphoma is a relatively uncommon malignancy that predominantly effects young adults. It became the first human cancer to be cured with combination chemotherapy. Unfortunately, many cured patients do not live their expected lifespan because of long-term lethal effects of therapy. Novel treatment strategies based on our understanding of Hodgkin's lymphoma biology are currently being explored to maintain the high cure rate without the added treatment related toxicity. Full text available free through Pubmed
Hodgkin’s Lymphoma: Biology and Treatment Strategies for Primary, Refractory, and Relapsed Disease
Hodgkin's lymphomas belong to the most curable tumor diseases in adults. About 80% of patients in all anatomical stages and of all histological subtypes can be cured with modern treatment strategies. In spite of the great clinical progress, the pathogenesis of this peculiar lymphoproliferative entity has not been elucidated completely up until now. Full text available free through Pubmed.
Hodgkin's lymphoma: evolving concepts with implications for practice.
Hodgkin's lymphoma is a unique neoplasm of B lymphocytes. Recent data provide new understandings of the pathogenesis and options for staging and therapy of the disease. Full text available free through Pubmed.
Current treatment and immunotherapy of Hodgkin's lymphoma.
The treatment of Hodgkin's lymphoma has changed significantly over the last decades, rendering this entity one of the most curable human cancers. To date, about 80% of patients achieve long-term disease-free survival. Current strategies in first-line treatment aim at further improving outcome and thereby preventing therapy-induced complications, such as infertility, cardiopulmonary toxicity, and secondary malignancies. Full text available free through Pubmed.
Salvage therapy in Hodgkin's lymphoma.
Hodgkin's disease is a rare malignancy that affects approximately 7,500 patients per year in the U.S., leading to an estimated 1,400 deaths. The relapse rate for this disease varies from around 5% for early-stage disease to 35% for patients with advanced disease. Full text available free through Pubmed.
The molecular mechanisms of classic Hodgkin's lymphoma.
This paper reviews several recent studies that for the first time implicate specific molecules in the pathogenesis of classic Hodgkin's lymphoma. Targeting these molecules could lead to the development of novel therapies for this disease. Full text available free through Pubmed.
Viruses and Hodgkin's lymphoma.
Hodgkin's lymphoma (HL) is unusual among human malignancies in that the epidemiology suggests an infectious aetiology. The Epstein-Barr virus (EBV) is associated with a proportion of cases and this association is believed to be causal. Full text available free through Pubmed.
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