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Macular Degeneration — Overview, Symptoms, Treatments, and Other Resources.
Macular Degeneration (also known as AMD)
Comprehensive Guides
Information on Macular Degeneration from NIH Senior Health
Age-related macular degeneration, also known as AMD, is an eye disease that affects the macula, a part of the retina. The retina sends light from the eye to the brain, and the macula allows you to see fine detail. Read more at NIH Senior Health.

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Information on Macular Degeneration from the University of Pittsburgh Medical Center
Adult Related Macular Degeneration

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Information on Macular Degeneration from Johns Hopkins Medical Center
Age-related macular degeneration (AMD) is the leading cause of severe, permanent vision loss in Americans over 50. More than 3.5 million people have early stages of macular degeneration. This disease of the macula, the central and most sensitive part of the retina, robs people of central vision. Left with only peripheral vision, they struggle to identify faces, read books and watch TV, because they can see out of the corners of their eyes, but not straight ahead. Read more at Johns Hopkins Medical Center.

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Macular degeneration: Essentials from Consumer Reports
What is it? What are the symptoms? How is it diagnosed? How common is it? What will happen? Questions to ask. Key points. More at ConsumerReports.org.

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Fact Sheets, Tutorials, Interactive Tools, and other Interesting Information
Macular Degeneration Vision Test
View ‘Interactive Macular Degeneration Vision Test’ presented by the Lasik Directory

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Videos and Podcasts
Podcast Podcast: Role of Nutrition and Dietary Supplements in AMD?
Listen to an academic, but informative, discussion on the role of nutrition and dietary supplements as revealed through clinical trials. Presented by Susan Bressler, MD, Julia G. Levy Professor of Opthalmology at Johns Hopkins School of Medicine.

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Podcast Podcast: Cochrane Review assesses treatments to tackle AMD
The Cochrane Review assesses treatments to tackle one of the common reasons for vision loss when people get older. Magdalena Krzystolik from Providence in the United States describes what she and Satyanarayana S. Vedula found.

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Video Video: Coping with Macular Degeneration
View a five-minute video prepared by the National Institutes of Health (NIH): ‘Coping with Macular Degeneration’

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Video Video: Living with macular degeneration
View a 2.5 minute video prepared by the National Institutes of Health (NIH): ‘Living with macular degeneration’

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Video Video: Animation of Wet and Dry Macular Degeneration
View a one-minute video on macular degeneration prepared by the American Macular Degeneration Foundation (AMDF): ‘Animation of Wet and Dry Macular Degeneration’

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Video Video: Blindness
View a short video on blindness prepared by the American Macular Degeneration Foundation (AMDF).

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Video Video: What a Person with AMD Sees
View a short video on macular degeneration prepared by the American Macular Degeneration Foundation (AMDF): ‘What a Person with AMD Sees – Joan W. Miller, M.D’

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Forums & Support Communities


Clinical Practice Guidelines
Ranibizumab and pegaptanib for the treatment of age-related macular degeneration
Ranibizumab, within its marketing authorisation, is recommended as an option for the treatment of wet age-related macular degeneration if: See National Guideline Clearinghouse major recommendations.

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Age-related macular degeneration
This guideline updates a previous version: American Academy of Ophthalmology (AAO). See National Guideline Clearinghouse major recommendations. Read full text at National Guideline Clearinghouse.

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Important Articles from Medical Journals
Reducing vision loss in chronic eye disease
BACKGROUND: Ocular disease in its early stages may be asymptomatic and insidious. Three of the leading causes of visual loss are cataract, age related macular degeneration and glaucoma. Full text of this abstract is available free through PubMed.

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Ranibizumab monotherapy for sub-foveal haemorrhage secondary to choroidal neovascularisation in age-related macular degeneration
In a retrospective review, the functional effects of intra-vitreal ranibizumab monotherapy in patients with sub-foveal haemorrhage secondary to choroidal neovascularisation (CNV) in age-related macular degeneration (ARMD) are reported. Full text of this abstract is available free through PubMed.

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Atrial Natriuretic Peptide Reduces Vascular Leakage and Choroidal Neovascularization
Atrial natriuretic peptide (ANP) is a hormone with diuretic, natriuretic, and vasodilatory properties. ANP blocks vascular endothelial growth factor (VEGF) production and signaling in vitro; however, its role in vascular leakage and angiogenesis is unknown. Full text of this abstract is available free through PubMed.

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Dietary n-3 PUFA Vascular Targeting and the Prevention of Tumor Growth and Age-Related Macular Degeneration
The protective role of dietary n-3 polyunsaturated fatty acids (PUFAs) against cardiovascular diseases has been partly related to their ability to modulate the risk condition known as "endothelial dysfunction", by reverting the endothelial alterations associated to it (reduced vascular reactivity, the proinflammatory state, and the prothrombotic properties). Full text of this abstract is available free through PubMed.

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Association between dietary fat intake and age-related macular degeneration in the Carotenoids in Age-Related Eye Disease Study (CAREDS): an ancillary study of the Women's Health Initiative
OBJECTIVE: To evaluate the relationships between the amount and type of dietary fat and intermediate age-related macular degeneration (AMD). DESIGN: Women aged 50 to 79 years with high and low lutein intake from 3 sites of the Women's Health Initiative Observational Study were recruited into the Carotenoids in Age-Related Eye Disease Study. Full text of this abstract is available free through PubMed.

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Progression of age-related macular degeneration after cataract surgery
OBJECTIVE: To document age-related macular degeneration (AMD) progression after cataract surgery. METHODS: Surgeons prospectively enrolled patients with nonneovascular AMD who were awaiting cataract surgery. Fluorescein angiography was performed preoperatively and at the postoperative week 1, month 3, and month 12 visits. Full text of this abstract is available free through PubMed.

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Association of c3 gene polymorphisms with neovascular age-related macular degeneration in a Chinese population
PURPOSE: The purpose of this study was to determine whether the genetic polymorphisms of complement factor 3 (C3) are associated with neovascular age-related macular degeneration (AMD) in the Chinese population. Full text of this abstract is available free through PubMed.

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Retrospective review of the efficacy of topical bromfenac (0.09%) as an adjunctive therapy for patients with neovascular age-related macular degeneration
PURPOSE: The purpose of this study was to assess the efficacy of topical bromfenac (0.09%) as an adjunctive therapy for patients with neovascular age-related macular degeneration demonstrating persistent exudation despite monthly intravitreal antivascular endothelial growth factor therapy. Full text of this abstract is available free through PubMed.

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Vascular events in patients with age-related macular degeneration treated with intraocular bevacizumab
PURPOSE: The purpose of this study was to determine the incidence of vascular events in patients treated with intraocular injections of bevacizumab. Full text of this abstract is available free through PubMed.

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What an AMD Sufferer Might See
Source: Bausch & Lomb

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Prevalence of Age-Related Macular Degeneration Among Older Adults
Source: American Federation of Aging Research

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